Phelop may be available in the countries listed below.
Ingredient matches for Phelop
Felodipine is reported as an ingredient of Phelop in the following countries:
- Taiwan
International Drug Name Search
Phelop may be available in the countries listed below.
Felodipine is reported as an ingredient of Phelop in the following countries:
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Ceftriaxone Aguettant may be available in the countries listed below.
Ceftriaxone disodium salt (a derivative of Ceftriaxone) is reported as an ingredient of Ceftriaxone Aguettant in the following countries:
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Riduvir may be available in the countries listed below.
Aciclovir is reported as an ingredient of Riduvir in the following countries:
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Hefasolon may be available in the countries listed below.
Prednisolone is reported as an ingredient of Hefasolon in the following countries:
Prednisolone 21-(disodium phosphate) (a derivative of Prednisolone) is reported as an ingredient of Hefasolon in the following countries:
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Fulstan may be available in the countries listed below.
Falecalcitriol is reported as an ingredient of Fulstan in the following countries:
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Higan may be available in the countries listed below.
Scopolamine butylbromide (a derivative of Scopolamine) is reported as an ingredient of Higan in the following countries:
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Isilung may be available in the countries listed below.
Eprazinone dihydrochloride (a derivative of Eprazinone) is reported as an ingredient of Isilung in the following countries:
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Xatral SR may be available in the countries listed below.
Alfuzosin is reported as an ingredient of Xatral SR in the following countries:
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Methovate may be available in the countries listed below.
Betamethasone 17α-valerate (a derivative of Betamethasone) is reported as an ingredient of Methovate in the following countries:
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Ipratropium Teva Adultes may be available in the countries listed below.
Ipratropium Bromide monohydrate (a derivative of Ipratropium Bromide) is reported as an ingredient of Ipratropium Teva Adultes in the following countries:
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Bencyclano may be available in the countries listed below.
Bencyclano (DCIT) is also known as Bencyclane (Rec.INN)
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Glossary
DCIT | Denominazione Comune Italiana |
Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
Kétoconazole may be available in the countries listed below.
Kétoconazole (DCF) is known as Ketoconazole in the US.
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Glossary
DCF | Dénomination Commune Française |
Rapamune 1mg/ml oral solution.
Sirolimus
1. What Rapamune is and what it is used for
2. Before you take Rapamune
3. How to take Rapamune
4. Possible side effects
5. How to store Rapamune
6. Further information
Rapamune belongs to a group of medicines called immunosuppressants. It helps to control your body’s immune system after you have received an organ transplant. It is used to prevent your body from rejecting transplanted kidneys and is normally used with medicines called corticosteroids and initially with ciclosporin.
Your doctor will perform tests to monitor the levels of Rapamune in your blood. Your doctor will also perform tests to monitor your kidney function, your blood fat (cholesterol and/or triglycerides) levels and, possibly, your liver function, during therapy with Rapamune.
Exposure to sunlight and UV light should be limited by wearing protective clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer.
Please tell your doctor or pharmacist if you are taking, or have recently taken any other medicines, including those obtained without a prescription. Some medicines can interfere with the action of Rapamune. In particular, you should inform your doctor or pharmacist if you are taking any of the following:
The use of Rapamune may lead to increased blood concentrations of cholesterol and triglycerides that may require treatment. Medicines known as “statins” and “fibrates” used to treat elevated cholesterol and triglycerides have been associated with an increased risk of muscle breakdown (rhabdomyolysis). Please inform your doctor if you are taking drugs to lower your blood fats.
Rapamune should be taken consistently, either with or without food. Rapamune should be diluted only with water or orange juice. Do not take Rapamune with grapefruit juice.
You must use effective contraception methods during treatment with Rapamune and for 12 weeks after treatment has stopped. If you are unsure, or think you may have become pregnant, talk to your doctor.
Ask your doctor or pharmacist for advice before taking any medicine.
Decreased sperm count has been associated with the use of Rapamune and usually resolves after discontinuation.
It is not known whether Rapamune passes into breast milk. Patients taking Rapamune should discontinue breast-feeding.
There is limited experience with the administration of Rapamune in children and adolescents.
No specific studies on the effects of Rapamune on the ability to drive and use machines have been conducted. Although Rapamune treatment is not expected to affect your ability to drive, if you have any concerns please consult your doctor.
WARNING: This medicine contains 1.5% to 2.5% ethanol. Each 2 mg dose contains up to 50 mg of alcohol. Alcohol may be harmful for those suffering from alcoholism, epilepsy, brain injury or disease as well as for pregnant women and children. Alcohol may modify or increase the effect of other medicines.
Rapamune is for oral use only. Always take Rapamune exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
Your doctor will decide exactly what dose of Rapamune you must take and how often to take it. Follow your doctor’s instructions exactly and never change the dose yourself. Do not stop taking your medicine unless your doctor tells you to. If you stop taking your medicine, you risk losing your transplant.
Usually for an adult your doctor will give you an initial dose of 6 mg as soon as possible after the kidney transplant operation. Then you will need to take 2 mg of Rapamune each day, unless otherwise directed by your doctor. Your dose will be adjusted depending on the level of Rapamune in your blood. Your doctor will need to perform a blood test to measure Rapamune concentrations.
If you are also taking ciclosporin, then you must take the two medicines approximately 4 hours apart.
1. Remove the safety cap from the bottle by squeezing the tabs on the cap and twisting. Insert the syringe adapter into the bottle until it is flush with the top of the bottle. Do not attempt to remove the syringe adapter from the bottle once inserted.
2. With the plunger fully depressed, insert one of the dosing syringes into the opening in the adapter.
3. Withdraw the exact amount of Rapamune oral solution as prescribed by your doctor by gently pulling out the plunger of the dosing syringe until the bottom of the black line of the plunger is level with the appropriate mark on the dosing syringe. The bottle should remain in an upright position when withdrawing the solution. If bubbles form in the dosing syringe during withdrawal, empty the Rapamune solution back into the bottle and repeat the withdrawal procedure.
4. You may have been instructed to take your Rapamune oral solution at a particular time of day. If it is necessary to carry your medication with you, fill the dosing syringe to the appropriate mark and place a cap securely on it – the cap should snap into place. Then place the capped dosing syringe in the carrying case provided. Once in the syringe the medication may be kept at room temperature (not exceeding 25°C) or refrigerated and should be used within 24 hours.
Empty the contents of the dosing syringe into only a glass or plastic container holding at least 60 ml of water or orange juice. Stir well for one minute and drink immediately. Refill the glass with at least 120 ml of water or orange juice, stir well, and drink immediately. No other liquids, including grapefruit juice, should be used for dilution. The dosing syringe and cap are to be used once and then discarded.
When refrigerated the solution in the bottle may develop a slight haze. If this occurs, simply bring your Rapamune 1 mg/1 ml oral solution to room temperature and shake gently. The presence of this haze does not affect the quality of Rapamune.
If you have taken more medicine than you were told contact a doctor or go to the nearest hospital emergency department straight away. Always take the labelled medicine bottle with you, even if it is empty.
If you forget to take Rapamune, take it as soon as you remember, but not within 4 hours of the next dose of ciclosporin. After that, continue to take your medicines as usual. Do not take a double dose to make up for a forgotten dose, and always take Rapamune and ciclosporin approximately 4 hours apart. If you miss a dose of Rapamune completely, you should inform your doctor.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
Like all medicines, Rapamune can cause side effects, although not everybody gets them. However, since Rapamune is taken in combination with other medicines, the side effects cannot always be attributed with absolute certainty to Rapamune. When taken with medicines called calcineurin inhibitors (ciclosporin or tacrolimus), Rapamune may increase the risk of kidney damage with low blood platelets and low red blood cell counts with or without rash (thrombocytopenic purpura/haemolytic uraemic syndrome).
Immunosuppressants, including Rapamune, reduce your body’s own defence mechanisms to stop you rejecting your transplanted organ. Consequently your body will not be as good as normal at fighting infections. So if you are taking Rapamune you may therefore catch more infections than usual such as infections of the skin, mouth, stomach and intestines, lungs and urinary tract.
Possible side effects of Rapamune are listed according to the following categories:
Very common: more than 1 per 10
Common: less than 1 per 10 but more than 1 per 100
Uncommon: less than 1 per 100 but more than 1 per 1000
Rare: less than 1 per 1000
Very common: Fluid collection around the kidney, swelling of the extremities, fever, pain
Common: Impaired healing (this may include separation of the layers of a surgical wound or suture line), swelling, infections (including life-threatening infections)
Very common: Headache
Common: Rapid heart rate
Uncommon: Fluid collection in the sac around the heart that, in some cases, may decrease the heart's ability to pump blood
Very common: Increased blood pressure
Common: Blood clots in the legs
Uncommon: Blood clots in the lung
Very common: Abdominal pain, diarrhea, constipation, nausea
Common: Mouth sores, fluid collection in the abdomen
Uncommon: Inflammation of the pancreas
Very common: Low red blood cells, low blood platelets
Common: Kidney damage with low blood platelets and low red blood cell counts with or without rash (thrombocytopenic purpura/haemolytic uraemic syndrome), a reduced number of infection fighting cells in the blood (white blood cells), low levels of a type of white blood cells called neutrophils
Uncommon: Cancer of the lymph tissue (lymphoma/post-transplant lympho-proliferative disorder), combined lowering of red blood cells, white blood cells and blood platelets
Rare: Too much fluid collecting in the tissues due to irregular lymph function
Rare: Allergic reactions including those that are life-threatening
Very common: Elevated cholesterol, elevated blood sugar, elevated fat in the blood, low blood potassium, low blood phosphorus, elevated lactate dehydrogenase protein in the blood, elevated creatinine in the blood
Common: Diabetes, abnormal tests of liver function, elevated AST and/or ALT liver enzymes
Very common: Joint pain
Common: Deterioration of bone
Common: Pneumonia and other causes of inflammation that may lead to lung damage, fluid around the lung, nose bleeds
Uncommon: Bleeding from the lung.
Rare: Protein build-up in the air sacs of the lungs that may interfere with breathing
Very common: Acne
Common: Skin cancer, rash
Very common: Urinary tract infection
Common: Kidney infection; protein in the urine
Uncommon: Protein in the urine, occasionally severe and associated with side effects such as swelling
There is a general tendency for fluid to collect in various tissues.
Serious liver damage has also been reported.
Scarring in the kidney that may reduce kidney function has been reported.
The above side effects may require medical intervention and some may be life-threatening or fatal.
You should see your doctor immediately if you experience symptoms such as swollen face, tongue and/or pharynx (back of the mouth) and/or difficulties in breathing (angioedema), or a skin condition whereby the skin can peel off (exfoliative dermatitis). If you are concerned about any side effect or if you notice any other effects not mentioned in this leaflet, please inform your doctor or pharmacist.
Keep out of the reach and sight of children.
Do not use Rapamune after the expiry date which is stated on the carton after EXP:. The expiry date refers to the last day of that month.
Keep Rapamune oral solution in its original bottle in order to protect from light. Store in a refrigerator (2°C - 8°C). Once the bottle has been opened, the contents should be kept refrigerated and used within 30 days. If necessary, you may store the bottles at room temperature up to 25°C for a short period of time (no longer than 24 hours).
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
The active substance is sirolimus. Each ml of Rapamune contains 1 mg of sirolimus.
The other ingredients are:
Polysorbate 80 and phosal 50 PG (phosphatidylcholine, propylene glycol, monodiglycerides, ethanol (1.5% to 2.5%), soya fatty acids, and ascorbyl palmitate).
Rapamune oral solution is supplied in 60 ml amber glass bottles.
Or
For any information about this medicinal product, please contact the local representative of the Marketing Authorisation Holder.
This leaflet was last approved in: 07/2010
Detailed information on this medicine is available on the European Medicines Agency (EMA) website: http://www.emea.europa.eu
Doc ID 61545 (Clean version of 61544)
Petscription Triplegard may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Permethrin is reported as an ingredient of Petscription Triplegard in the following countries:
Piperonyl Butoxide is reported as an ingredient of Petscription Triplegard in the following countries:
Pyrethrin I is reported as an ingredient of Petscription Triplegard in the following countries:
Pyriproxyfen is reported as an ingredient of Petscription Triplegard in the following countries:
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In the US, Imotil (loperamide systemic) is a member of the drug class antidiarrheals and is used to treat Diarrhea, Diarrhea - Acute, Diarrhea - Chronic, Lymphocytic Colitis and Traveler's Diarrhea.
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Loperamide hydrochloride (a derivative of Loperamide) is reported as an ingredient of Imotil in the following countries:
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Gludex may be available in the countries listed below.
Rosiglitazone maleate (a derivative of Rosiglitazone) is reported as an ingredient of Gludex in the following countries:
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Butaro may be available in the countries listed below.
Butorphanol tartrate (a derivative of Butorphanol) is reported as an ingredient of Butaro in the following countries:
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Tenso Stop may be available in the countries listed below.
Fosinopril sodium salt (a derivative of Fosinopril) is reported as an ingredient of Tenso Stop in the following countries:
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Tipepidine Hibenzate may be available in the countries listed below.
Tipepidine Hibenzate (JAN) is also known as Tipepidine (Rec.INN)
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Glossary
JAN | Japanese Accepted Name |
Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
Ecelecort may be available in the countries listed below.
Mometasone 17-(2-furoate) (a derivative of Mometasone) is reported as an ingredient of Ecelecort in the following countries:
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Lidocaina + Adrenalina Pierrel may be available in the countries listed below.
Epinephrine bitartrate (a derivative of Epinephrine) is reported as an ingredient of Lidocaina + Adrenalina Pierrel in the following countries:
Lidocaine hydrochloride (a derivative of Lidocaine) is reported as an ingredient of Lidocaina + Adrenalina Pierrel in the following countries:
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Paracodina may be available in the countries listed below.
Benzoic Acid is reported as an ingredient of Paracodina in the following countries:
Dihydrocodeine tartrate (a derivative of Dihydrocodeine) is reported as an ingredient of Paracodina in the following countries:
Dihydrocodeine thiocyanate (a derivative of Dihydrocodeine) is reported as an ingredient of Paracodina in the following countries:
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Amerol may be available in the countries listed below.
Loperamide hydrochloride (a derivative of Loperamide) is reported as an ingredient of Amerol in the following countries:
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Captopril/Hydrochlorothiazide Teva may be available in the countries listed below.
Captopril is reported as an ingredient of Captopril/Hydrochlorothiazide Teva in the following countries:
Hydrochlorothiazide is reported as an ingredient of Captopril/Hydrochlorothiazide Teva in the following countries:
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Temperax may be available in the countries listed below.
Citalopram hydrobromide (a derivative of Citalopram) is reported as an ingredient of Temperax in the following countries:
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Tramagit may be available in the countries listed below.
Tramadol hydrochloride (a derivative of Tramadol) is reported as an ingredient of Tramagit in the following countries:
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Cetrimonium Chloride may be available in the countries listed below.
Cetrimonium Chloride (BAN) is also known as Cetrimonium (DCF)
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BAN | British Approved Name |
DCF | Dénomination Commune Française |
Calciumfolinat Medipolis may be available in the countries listed below.
Calcium Folinate is reported as an ingredient of Calciumfolinat Medipolis in the following countries:
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Klarifer may be available in the countries listed below.
Loratadine is reported as an ingredient of Klarifer in the following countries:
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In the US, Aranesp (darbepoetin alfa systemic) is a member of the drug class recombinant human erythropoietins and is used to treat Anemia Associated with Chronic Renal Failure and Anemia - Chemotherapy Induced.
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UK matches:
Darbepoetin Alfa is reported as an ingredient of Aranesp in the following countries:
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SPC | Summary of Product Characteristics (UK) |
Cytostar may be available in the countries listed below.
Cytarabine is reported as an ingredient of Cytostar in the following countries:
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Chilvax may be available in the countries listed below.
Carbocisteine is reported as an ingredient of Chilvax in the following countries:
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Rutovit C may be available in the countries listed below.
Ascorbic Acid is reported as an ingredient of Rutovit C in the following countries:
Rutoside is reported as an ingredient of Rutovit C in the following countries:
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Insulin Novolin 50R may be available in the countries listed below.
Insulin Injection, Biphasic Isophane human (a derivative of Insulin Injection, Biphasic Isophane) is reported as an ingredient of Insulin Novolin 50R in the following countries:
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Axtil may be available in the countries listed below.
Ramipril is reported as an ingredient of Axtil in the following countries:
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Cupanol may be available in the countries listed below.
Paracetamol is reported as an ingredient of Cupanol in the following countries:
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Eryacnen may be available in the countries listed below.
Erythromycin is reported as an ingredient of Eryacnen in the following countries:
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Piroxicam Vannier may be available in the countries listed below.
Piroxicam is reported as an ingredient of Piroxicam Vannier in the following countries:
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Ketlac may be available in the countries listed below.
Ketorolac tromethamine (a derivative of Ketorolac) is reported as an ingredient of Ketlac in the following countries:
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Prasugrel hydrochloride may be available in the countries listed below.
Prasugrel hydrochloride (USAN) is known as Prasugrel in the US.
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USAN | United States Adopted Name |
Miranax may be available in the countries listed below.
Naproxen sodium salt (a derivative of Naproxen) is reported as an ingredient of Miranax in the following countries:
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Aspen Lamzid may be available in the countries listed below.
Lamivudine is reported as an ingredient of Aspen Lamzid in the following countries:
Zidovudine is reported as an ingredient of Aspen Lamzid in the following countries:
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Bupivacaïne Mylan may be available in the countries listed below.
Bupivacaine hydrochloride (a derivative of Bupivacaine) is reported as an ingredient of Bupivacaïne Mylan in the following countries:
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Etacid may be available in the countries listed below.
Mometasone 17-(2-furoate) (a derivative of Mometasone) is reported as an ingredient of Etacid in the following countries:
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Fluoxetina Stada may be available in the countries listed below.
Fluoxetine hydrochloride (a derivative of Fluoxetine) is reported as an ingredient of Fluoxetina Stada in the following countries:
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Benazeplus Stada may be available in the countries listed below.
Benazepril hydrochloride (a derivative of Benazepril) is reported as an ingredient of Benazeplus Stada in the following countries:
Hydrochlorothiazide is reported as an ingredient of Benazeplus Stada in the following countries:
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Lovatex may be available in the countries listed below.
Lovastatin is reported as an ingredient of Lovatex in the following countries:
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Thymazen may be available in the countries listed below.
Tymazoline hydrochloride (a derivative of Tymazoline) is reported as an ingredient of Thymazen in the following countries:
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Lorfenamin may be available in the countries listed below.
Loxoprofen sodium salt (a derivative of Loxoprofen) is reported as an ingredient of Lorfenamin in the following countries:
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Entocord Orifarm may be available in the countries listed below.
Budesonide is reported as an ingredient of Entocord Orifarm in the following countries:
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Loradexan may be available in the countries listed below.
Dexamethasone is reported as an ingredient of Loradexan in the following countries:
Loratadine is reported as an ingredient of Loradexan in the following countries:
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Tylo-Kel may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Tylosin tartrate (a derivative of Tylosin) is reported as an ingredient of Tylo-Kel in the following countries:
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Laxopol may be available in the countries listed below.
Docusate Sodium is reported as an ingredient of Laxopol in the following countries:
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CB Scopola may be available in the countries listed below.
Scopolamine butylbromide (a derivative of Scopolamine) is reported as an ingredient of CB Scopola in the following countries:
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Lundiran may be available in the countries listed below.
Naproxen is reported as an ingredient of Lundiran in the following countries:
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AHX Iodine may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Iodine is reported as an ingredient of AHX Iodine in the following countries:
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Pulmicort Turbuhaler Paranova may be available in the countries listed below.
Budesonide is reported as an ingredient of Pulmicort Turbuhaler Paranova in the following countries:
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Elzer may be available in the countries listed below.
Donepezil hydrochloride (a derivative of Donepezil) is reported as an ingredient of Elzer in the following countries:
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Glicirex may be available in the countries listed below.
Gliclazide is reported as an ingredient of Glicirex in the following countries:
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Clargotil may be available in the countries listed below.
Loratadine is reported as an ingredient of Clargotil in the following countries:
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In some countries, this medicine may only be approved for veterinary use.
In the US, Ketoprofen (ketoprofen systemic) is a member of the drug class nonsteroidal anti-inflammatory agents and is used to treat Back Pain, Fever, Frozen Shoulder, Gout - Acute, Osteoarthritis, Pain, Period Pain, Rheumatoid Arthritis and Sciatica.
US matches:
Rec.INN
M01AE03,M02AA10
0022071-15-4
C16-H14-O3
254
Analgesic, antipyretic and anti-inflammatory agent
Non-steroidal anti-inflammatory drug, NSAID
Benzeneacetic acid, 3-benzoyl-α-methyl-
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Glossary
BAN | British Approved Name |
DCF | Dénomination Commune Française |
DCIT | Denominazione Comune Italiana |
IS | Inofficial Synonym |
JAN | Japanese Accepted Name |
OS | Official Synonym |
PH | Pharmacopoeia Name |
Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
USAN | United States Adopted Name |
Poncoquin may be available in the countries listed below.
Ofloxacin is reported as an ingredient of Poncoquin in the following countries:
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In some countries, this medicine may only be approved for veterinary use.
Rec.INN
0003704-09-4
C20-H30-O2
302
Anabolic
Androgen
Estr-4-en-3-one, 17-hydroxy-7,17-dimethyl-, (7α,17ß)-
International Drug Name Search
Glossary
BAN | British Approved Name |
DCF | Dénomination Commune Française |
IS | Inofficial Synonym |
OS | Official Synonym |
PH | Pharmacopoeia Name |
Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
USAN | United States Adopted Name |
Tarizart may be available in the countries listed below.
Ofloxacin is reported as an ingredient of Tarizart in the following countries:
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Trerief may be available in the countries listed below.
Zonisamide is reported as an ingredient of Trerief in the following countries:
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Mucosolvan may be available in the countries listed below.
Ambroxol is reported as an ingredient of Mucosolvan in the following countries:
Ambroxol hydrochloride (a derivative of Ambroxol) is reported as an ingredient of Mucosolvan in the following countries:
Bromhexine hydrochloride (a derivative of Bromhexine) is reported as an ingredient of Mucosolvan in the following countries:
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